List of Publications
Update: 21.06.2017

Researcher Identifiers
Megan Cross
Assoc Prof Andreas Hofmann


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List of Publications


Articles
100. Preston, S., Korhonen, P.K., Mouchiroud, L., Cornaglia, M., McGee, S.L., Young, N.D., Davis, R.A., Crawford, S., Nowell, C., Ansell, B.R.E., Fisher, G.M., Andrews, K.T., Chang, B., Gijs, M.A.M., Sternberg, P.W., Auwerx, J., Baell, J., Hofmann, A., Jabbar, A. & Gasser, R.B. (2017)
Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
FASEB J., in press.
DOI | More |
99. Preston, S., Jiao, Y., Baell, J.B., Keiser, J., Crawford, S., Koehler, A.V., Wang, T., Simpson, M.M., Kaplan, R.M., Cowley, K.J., Simpson, K.J., Hofmann, A., Jabbar, A. & Gasser, R.B. (2017)
Screening of the 'Open Scaffolds' collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes.
Int. J. Parasitol. Drug, in press.
DOI | More |
98. Wibowo, M., Wang, Q., Holst, J., White, J.M., Hofmann, A. & Davis, R. (2017)
Celastrofurans A-G: Dihydro-β-agarofurans from the Australian rainforest vine Celastrus subspicata and their inhibitory effect on leucine transport in prostate cancer cells.
J. Nat. Prod. 80, 1918-1925.
DOI | PubMed | More |
97. Jiao, Y., Preston, S., Song, H., Jabbar, A., Liu, Y., Baell, J., Hofmann, A., Hutchinson, D., Wang, T., Koehler, A., Fisher, G., Andrews, K., Willis, P., Palmer, M., Wells, T., Wang, Q. & Gasser, R.B. (2017)
Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus.
Parasites & Vectors 10, 272.
DOI | PubMed | More |
96. Dallaston, M.A., Rajan, S., Chekaiban, J., Wibowo, M., Cross, M., Coster, M.J., Davis, R.A. & Hofmann, A. (2017)
Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c.
MedChemComm 8, 1318-1321.
DOI | More |
95. Türk, M., Schröder, R., Khuller, K., Hofmann, A., Berwanger, C., Ludolph, A.C., Dekomien, G., Müller, K., Weishaupt, J.H., Thiel, C.T. & Clemen, C. (2017)
Genetic analysis of VCP and WASH-complex genes in a German cohort of sporadic ALS-FTD patients.
Neurobiol. Aging 56, 213.e1-213.e5.
DOI | PubMed | More |
94. Cross, M., Rajan, S., Chekaiban, J., Saunders, J., Hamilton, C., Kim, J.-S., Coster, M. J., Gasser, R. B. & Hofmann, A. (2017)
Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases.
Sci. Rep. 7, 2015.
DOI | PubMed | Publisher | More |
93. Cross, M., Lepage, R., Rajan, S., Biberacher, S., Young, N.D., Kim, B.-N., Coster, M.J., Gasser, R.B., Kim, J.-S. & Hofmann, A. (2017)
Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings.
FASEB J. 31, 920-926.
DOI | PubMed | More |
92. Wibowo, M., Wang, Q., Holst, J., White, J.M., Hofmann, A. & Davis, R. (2016)
Dihydro-β-agarofurans from the Australian endemic rainforest plant Denhamia pittosporoides inhibit leucine transport in prostate cancer cells.
Asian J. Org. Chem. 5, 1461-1466.
DOI | More |
91. Ströhlein, A.J., Young, N.D., Hall, R.S., Korhonen, P.K., Hofmann, A., Sternberg, P.W., Jabbar, A. & Gasser, R.B. (2016)
CAP protein superfamily members in Toxocara canis.
Parasites & Vectors 9, 360.
DOI | PubMed | More |
90. Preston, S., Luo, J., Zhang, Y., Jabbar, A., Crawford, S., Baell, J., Hofmann, A., Hu, M., Zhou, H.-B. & Gasser, R.B. (2016)
Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus.
Parasites & Vectors 9, 346.
DOI | PubMed | More |
89. McNeilly, C., Cosh, S., Vu, T., Nichols, J., Henningham, A., Hofmann, A., Fane, A., Smeesters, P.R., Rush, C.M., Hafner, L.M., Ketheesan, N., Sriprakash, K.S. & McMillan, D.J. (2016)
Predicted coverage and immuno-safety of a recombinant C-repeat region based Streptococcus pyogenes vaccine candidate.
PLoS ONE 11, e0156639.
DOI | PubMed | More |
88. Wibowo, M., Levrier, C., Sadowski, M.C., Nelson, C.C., Wang, Q., Holst, J., Healy, P.C., Hofmann, A. & Davis, R.A. (2016)
Bioactive dihydro-β-agarofuran sesquiterpenes from the Australian rainforest plant Maytenus bilocularis.
J. Nat. Prod. 79, 1445-1453.
DOI | PubMed | More |
87. Rijal, R., Arhzaouy, K., Strucksberg, K.-H., Cross, M., Hofmann, A., Schröder, R., Clemen, C.S. & Eichinger, L. (2016)
Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerization of p97 hexamers.
Eur. J. Cell Biol. 95, 195-207.
DOI | PubMed | More |
86. Ströhlein , A.J., Young, N.D., Korhonen, P.K., Jabbar, A., Hofmann, A., Sternberg, P.W. & Gasser, R.B. (2015)
The Haemonchus contortus kinome — a resource for fundamental molecular investigations and drug discovery.
Parasites & Vectors 8, 623.
DOI | PubMed | More |
85. Korhonen, P.K., Pozio, E., La Rosa, G., Chang, B., Koehler, A.V., Hoberg, E.P., Boag, P.R., Tan, P., Jex, A.R., Hofmann, A., Sternberg, P.W., Young, N.D. & Gasser, R.B. (2016)
Phylogenomic and biogeographic reconstruction of the Trichinella complex.
Nat. Commun. 7, 10513.
DOI | PubMed | More |
84. Young, N.D., Chan, K.-G., Korhonen, P.K., Chong, T.M., Han-Jen, R., Mohandas, N., Koehler, A.V., Lim, Y.-L., Hofmann, A., Jex, A.R., Qian, B., Chilton, N.B., Gobert, G.N., McManus, D., Tan, P., Webster, B.L., Rollinson, D. & Gasser, R.B. (2015)
Exploring molecular variation in Schistosoma japonicum in China.
Sci. Rep. 5, 17345.
DOI | PubMed | More |
83. Ströhlein, A.J., Young, N.D., Jex, A.R., Sternberg, P.W., Tan, P., Boag, P.R., Hofmann, A. & Gasser, R.B. (2015)
Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets.
Sci. Rep. 5, 17759.
DOI | PubMed | More |
82. Preston, S., Jabbar, A., Nowell, C., Joachim, A., Ruttkowski, B., Cardno, T., Hofmann, A. & Gasser, R.B. (2016)
Practical and low cost whole-organism motility assay: a step-by-step protocol.
Mol. Cell. Probes 30, 13-17.
DOI | PubMed | More |
81. Nawaratna, S.S.K., Gobert, G.N., Willis, C., Mulvenna, J., Hofmann, A., McManus, D.P. & Jones, M.K. (2015)
Lysosome-associated membrane glycoprotein (LAMP) - preliminary study on a hidden antigen target for vaccination against schistosomiasis.
Sci. Rep. 5, 15069.
DOI | PubMed | More |
80. Clemen, C.S., Marko, M., Strucksberg, K.-H., Behrens, J., Wittig, I., Gärtner, L., Winter, L., Chevessier, F., Matthias, J., Türk, M., Tangavelou, K., Schütz, J., Arhzaouy, K., Klopffleisch, K., Hanisch, F.-G., Rottbauer, W., Blümcke, I., Just, S., Eichinger, L., Hofmann, A. & Schröder, R. (2015)
VCP and PSMF1: antagonistic regulators of proteasome activity.
Biochem. Biophys. Res. Comm. 463, 1210-1217.
DOI | PubMed | More |
79. Amani, P., Sneyd, T., Preston, S., Young, N.D., Mason, L., Bailey, U.-M., Baell, J., Camp, D., Gasser, R.B., Gorse, A.-D., Taylor, P. & Hofmann, A. (2015)
A practical tool for small-molecule compound appraisal.
J. Cheminformatics 7, 28.
DOI | PubMed | More |
78. Nienaber, L., Cave-Freeman, E., Cross, M., Mason, L., Bailey, U.-M., Amani, P., Davis, R., Taylor, P. & Hofmann, A. (2015)
Chemical probing suggests Redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
FEBS J. 282, 2708-2721.
DOI | PubMed | More |
77. Anstead, C.A., Korhonen, P.K., Young, N.D., Hall, R.S., Jex, A.R., Murali, S.C., Hughes, D.S., Lee, S.F., Perry, T., Ströhlein, A.J., Ansell, B.R.E., Breugelmans, B., Hofmann, A., Qu, J., Dugan, S., Lee, S.L., Chao, H., Dinh, H., Han, Y., Doddapaneli, H.V., Worley, K.C., Muzny, D.M., Ioannidis, P., Waterhouse, R.M., Zdobnov, E.M., James, P.J., Bagnall, N.H., Kotze, A.C., Gibbs, R.A., Richards, S., Batterham, P. & Gasser, R.B. (2015)
Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.
Nat. Commun. 6, 7344.
DOI | PubMed | More |
76. Breugelmans, B., Ansell, B.R.E., Young, N.D., Amani, P., Novakovic, S., Ströhlein, A., Sternberg, P.W., Jex, A.R., Boag, P.R., Hofmann, A. & Gasser, R.B. (2015)
Flatworms have lost the right open reading frame kinase 3 gene during evolution.
Sci. Rep. 5, 9417.
DOI | PubMed | More |
75. Preston, S., Jabbar, A., Nowell, C., Joachim, A., Ruttkowski, B., Baell, J., Cardno, T., Korhonen, P.K., Piedrafta, D., Jex, A.R., Hofmann, A. & Gasser, R.B. (2015)
Low cost whole-organism screening of compounds for anthelmintic activity.
Int. J. Parasitol. 45, 333-343.
DOI | PubMed | More |
74. Mendes, T.K., Novakovic, S., Raymant, G., Bertram, S.E., Esmaillie, R., Nadarajan, S., Breugelmans, B., Hofmann, A., Gasser, R.B., Colaiácovo, M.P. & Boag, P.R. (2015)
Investigating the role of RIO protein kinases in Caenorhabditis elegans.
PLoS ONE 10, e0117444.
DOI | PubMed | More |
73. Zhu, X.-Q., Korhonen, P., Cai, H., Young, N., Nejsum, P., von Samson-Himmelstjerna, G., Boag, P., Tan, P., Fang, X., Hall, R., Hofmann, A., Sternberg, P., Jex, A. & Gasser, R.B. (2015)
Genetic blueprint of the zoonotic pathogen Toxocara canis.
Nat. Commun. 6, 6145.
DOI | PubMed | More |
72. Tribolet, L., Cantacessi, C., Pickering, D., Navarro, S., Doolan, D., Trieu, A., Fei, H., Chao, Y., Hofmann, A., Gasser, R.B., Giacomin, P.R. & Loukas, A. (2015)
Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B cell receptor signaling.
J. Inf. Dis. 211, 416-425.
DOI | PubMed | More |
71. von Gnielinski, N., Nienaber, L., Mason, L., Ellis, S., Triccas, J.A., Davis, R.A. & Hofmann, A. (2014)
Non-classical β-carbonic anhydrase inhibitors - Towards novel anti-mycobacterials.
Med. Chem. Commun. 5, 1563-1566.
DOI | More |
70. Breugelmans, B., Jex, A.R., Korhonen, P.K., Mangiola, S., Young, N.D., Sternberg, P.W., Boag, P.R., Hofmann, A. & Gasser, R.B. (2014)
Bioinformatic exploration of RIO protein kinases of parasitic and free-living nematodes.
Int. J. Parasitol. 44, 827-836.
DOI | PubMed | More |
69. Rebaud, S., Wang, C.K., Sarkis, J., Mason, L., Simon, A., Blum, L.J., Hofmann, A. & Girard-Egrot, A. (2014)
Specific interaction of N-terminal polybasic cluster to PIP2 increases the kinetic rate of membrane binding of VILIPs, a subfamily of Neuronal Calcium Sensor Proteins.
Biochim. Biophys. Acta - Biomembranes 1838, 2698-2707.
DOI | PubMed | More |
68. Wang, C.K. & Hofmann, A. (2015)
An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements.
3Biotech 5, 87-92.
DOI | More |
67. Young, N.D., Nagarajan, N., Joyce Lin, S., Korhonen, P.K., Jex, A.R., Hall, R.S., Safavi-Hemani, H., Kaewkong, W., Bertrand, D., Gao, S., Seet, O., Wongkham, S., Tean Teh, B., Wongkham, C., Maleewong Intapan, P., Maleewong, W., Yang, X., Hu, M., Wang, Z., Hofmann, A., Sternberg, P.W., Tan, P., Wang, J. & Gasser, R.B. (2014)
The Opisthorchis viverrini genome provides insights into life in the bile duct.
Nat. Commun. 5, 4378.
DOI | PubMed | More |
66. Jex, A.R., Nejsum, P., Schwarz, E.M., Hu, L., Young, N.D., Hall, R.S., Korhonen, P.K., Liao, S., Thamsborg, S., Xia, J., Xu, P., Wang, S., Scheerlinck, J.-P.Y., Hofmann, A., Sternberg, P.W., Wang, J. & Gasser, R.B. (2014)
Genome and transcriptome of the porcine whipworm Trichuris suis.
Nat. Genet. 46, 701-706.
DOI | PubMed | More |
65. Reynolds, S.L., Pike, R.N., Mika, A., Blom, A.M., Hofmann, A., Wijeyewickrema, L.C. & Fischer, K. (2014)
Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin.
PLoS Negl. Trop. Dis. 8, e2872.
DOI | PubMed | More |
64. Rebaud, S., Simon, A., Wang, C.K., Mason, L., Blum, L., Hofmann, A. & Girard-Egrot, A. (2014)
Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers.
PLoS ONE 9, e93948.
DOI | PubMed | More |
63. Mason, L., Tribolet, L., Simon, A., von Gnielinski, N., Nienaber, L., Taylor, P., Willis, C., Jones, M.K., Sternberg, P.W., Gasser, R.B., Loukas, A. & Hofmann, A. (2014)
Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2.
Int. J. Biochem. Cell Biol. 50, 146-155.
DOI | PubMed | More |
62. Hofmann, A. & Whitten, A. (2014)
Two practical Java software tools for small-angle X-ray scattering analysis of biomolecules.
J. Appl. Crystallogr. 47, 810-815.
DOI | More |
61. Mangiola, S, Young, N.D., Sternberg, P.W., Strube, C., Korhonen, P.K., Hofmann, A., Mitreva, M., Scheerlinck, J.-P., Jex, A.R. & Gasser, R.B. (2014)
Comparative analyses of the transcriptomes of Dictyocaulus filaria and D. viviparus adults elucidate key molecules involved in parasite-host interactions.
Int. J. Parasitol. 44, 251-261.
DOI | PubMed | More |
60. Leow, C.Y., Willis, C., Osman, A., Mason, L., Simon, A., Gasser, R.B., Smith, B., Jones, M.K. & Hofmann, A. (2014)
Crystal structure and immunological properties of the first annexin from Schistosoma mansoni.
FEBS J. 281, 1209-1225.
DOI | PubMed | More |
59. Cantacessi, C., Seddon, J.M., Miller, T.L., Leow, C.Y., Thomas, L., Mason, L., Willis, C., Walker, G., Loukas, A., Gasser, R.B., Jones, M.K. & Hofmann, A. (2013)
A genome-wide analysis of annexins from parasitic organisms and their vectors.
Sci. Rep. 3, 2893.
DOI | PubMed | More |
58. Schwarz, E.M., Korhonen, P.K., Campbell, B.E., Young, N.D., Jex, A.R., Jabbar, A., Hall, R.S., Mondal, A., Howe, A.C., Pell, J., Hofmann, A., Boag, P.R., Zhu, X.-Q., Gregory, T.R., Loukas, A., Williams, B.A., Antoshechkin, I., Brown, C.T., Sternberg, P.W. & Gasser, R.B. (2013)
The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus.
Genome Biol. 14, 1-31.
DOI | PubMed | More |
57. Cantacessi, C., Hofmann, A., Pickering, D., Navarro, S., Mitreva, M. & Loukas, A. (2013)
TIMPs of parasitic helminths--a large-scale analysis of high-throughput sequence datasets.
Parasites & Vectors 6, 156.
DOI | PubMed | PDF | More |
56. Karl, S., Gutiérrez, L., Lucyk-Maurer, R., Kerr, R., Candido, R.R.F., Toh, S.Q., Saunders, M., Shaw, J.A., Suvorova, A., Hofmann, A., House, M.J., Woodward, R.C., Graeff-Teixera, C., St. Pierre, T.G. & Jones, M.K. (2013)
The iron distribution and magnetic properties of schistosome eggshells: implications for improved diagnostics.
PLoS Negl. Trop. Dis. 7, e2219.
DOI | PubMed | More |
55. Cantacessi, C., Mulvenna, J., Young, N.D., Kasny, M., Horak, P., Aziz, A., Hofmann, A., Loukas, A. & Gasser, R.B. (2012)
A deep exploration of the transcriptome and excretory/secretory proteome of adult Fascioloides magna.
Mol. Cell. Prot. 11, 1340-1353.
DOI | PubMed | More |
54. Weeratunga, S.K., Hu, N.J., Simon, A. & Hofmann, A. (2012)
SDAR: a practical tool for graphical analysis of two-dimensional data.
BMC Bioinformatics 13, 201.
DOI | PubMed | Publisher | More |
53. Weeratunga, S.K., Osman, A., Hu, N.J., Wang, C.K., Mason, L., Svärd, S., Hope, G., Jones, M.K. & Hofmann, A. (2012)
alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.
J. Mol. Biol. 423, 169-181.
DOI | PubMed | More |
52. Cantacessi, C., Hofmann, A., Young, N.D., Broder, U., Hall, R.S., Loukas, A. & Gasser, R.B. (2012)
Insights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasets.
PLoS ONE 7, e31164.
DOI | PubMed | More |
51. Wang, C.K., Broder, U., Weeratunga, S.K., Gasser, R.B., Loukas, A. & Hofmann, A. (2012)
SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments.
Bioinformatics 28, 1026-1027.
DOI | PubMed | More |
50. Bauer, M., Georgousakis, M., Vu, T., Henningham, A., Hofmann, A., Rettel, M., Hafner, L., Sriprakash, S. & McMillan, D. (2012)
Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.
Vaccine 30, 2197-2205.
DOI | PubMed | More |
49. Salmon, A.J., Williams, M.L., Hofmann, A. & Poulsen, S.A. (2012)
Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors.
Chem. Commun. 48, 2328-2330.
DOI | PubMed | More |
48. Xavier, C.P., Rastetter, R.H., Blömacher, M., Stumpf, M., Himmel, M., Morgan, R.O., Fernandez, M.P., Wang, C., Osman, A., Miyata, Y., Gjerset, R.A., Eichinger, L., Hofmann, A., Linder, S., Noegel, A.A. & Clemen, C.S. (2012)
Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.
Sci. Rep. 2, 241.
DOI | PubMed | More |
47. Wang, C.K., Weeratunga, S.K., Pacheco, C.M. & Hofmann, A. (2012)
DMAN: a Java tool for analysis of multi-well differential scanning fluorimetry experiments.
Bioinformatics 28, 439-440.
DOI | PubMed | More |
46. Young, N.D., Jex, A.R., Li, B., Liu, S., Yang, L., Xiong, Z., Li, Y., Cantacessi, C., Hall, R.S., Xu, X., Chen, F., Wu, X., Zerlotini, A., Oliveira, G., Hofmann, A., Zhang, G., Fang, X., Kang, Y., Campbell, B.E., Loukas, A., Ranganathan, S., Rollinson, D., Rinaldi, G., Brindley, P.J., Yang, H., Wang, J., Wang, J. & Gasser, R.B. (2012)
Whole-genome sequence of Schistosoma haematobium.
Nat. Genet. 44, 221-225.
DOI | PubMed | More |
45. Kori, L.D., Hofmann, A. & Patel, B.K.C. (2012)
Expression, purification, crystallization and preliminary X-ray diffraction analysis of a ribokinase from the thermohalophile, Halothermothrix orenii.
Acta Crystallogr. F 68, 240-243.
DOI | PubMed | More |
44. Wang, C.K., Simon, A., Jessen, C.M., Oliveira, C.L.P., Mack, L., Braunewell, K., Ames, J.B., Pedersen, J.S. & Hofmann, A. (2011)
Divalent cations and redox conditions regulate the molecular structure and function of Visinin-like Protein 1.
PLoS ONE 6, e26793.
DOI | PubMed | More |
43. Willis, C., Wang, C.K., Osman, A., Simon, A., Pickering, D., Mulvenna, J., Riboldi-Tunicliffe, A., Jones, M.K., Loukas, A. & Hofmann, A. (2011)
Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.
PLoS ONE 6, e25369.
DOI | PubMed | More |
42. Davis, R.A., Hofmann, A., Osman, A., Hall, R.A., Mühlschlegel, F.A., Vullo, D., Innocenti, A., Supuran, C.T. & Poulsen, S.-A. (2011)
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.
J. Med. Chem. 54, 1682-1692.
DOI | PubMed | More |
41. Kori, L.D., Hofmann, A. & Patel, B.K.C. (2011)
Expression, purification and preliminary crystallographic analysis of the recombinant β- glucosidase (BglA) from halothermophile Halothermothrix orenii.
Acta Crystallogr. F 67, 111-113.
DOI | PubMed | More |
40. Nolan, M.J., Hofmann, A., Jex, A.R. & Gasser, R.B. (2010)
A theoretical study to establish the relationship between the three-dimensional structure of triose-phosphate isomerase of Giardia duodenalis and point mutations in the respective gene.
Mol. Cell. Probes 24, 281-285.
DOI | PubMed | More |
39. Clemen, C.S, Tangavelou, K., Strucksberg, K.-H., Just, S., Gaertner, L., Regus-Leidig, H., Stumpf, M., Reimann, J., Coras, R., Morgan, R.O., Fernandez, M.-P., Hofmann, A., Müller, S., Schoser, B., Hanisch, F.-G., Rottbauer, W., Blümcke, I., von Hörsten, S., Eichinger, L. & Schröder, R. (2010)
Strumpellin is a Novel VCP Binding Protein interlinking Hereditary Spastic Paraplegia with Protein Aggregation Diseases.
Brain 133, 2920-2941.
DOI | PubMed | More |
38. Campbell, B.E., Rabelo, E.M., Hofmann, A., Hu, M. & Gasser, R.B. (2010)
Characterization of a Caenorhabditis elegans Glc seven-like phosphatase (gsp) orthologue from Haemonchus contortus (Nematoda).
Mol. Cell. Probes 24, 178-189.
DOI | PubMed | More |
37. Lopez, M., Paul, B., Hofmann, A., Morizzi, J., Wu, Q.K., Charman, S.A., Innocenti, A., Vullo, D., Supuran, C.T. & Poulsen, S.-A. (2009)
S-glycosyl primary sulfonamides - A new structural class for selective inhibition of cancer-associated carbonic anhydrases.
J. Med. Chem. 52, 6421-6432.
DOI | PubMed | More |
36. Georgousakis, M., Hofmann, A., McMillan, D., Batzloff, M. & Sriprakash, S. (2009)
Structural optimisation of a conformational epitope improves antigenicity when expressed as a recombinant fusion protein.
Vaccine 27, 6799-6806.
DOI | PubMed |
35. Braunewell, K.-H., Paul, B., Altarche-Xifro, W., Noack, C., Lange, K. & Hofmann, A. (2010)
Interactions of Visinin-like Proteins with Phospho-inositides.
Aust. J. Chem. 63, 350-356.
DOI |
34. Xavier, C.P., Rastetter, R.H., Stumpf, M., Rosentreter, A., Müller, R., Reimann, J., Cornfine, S., Linder, S., van Vliet, V., Hofmann, A., Morgan, R.O., Fernandez, M.P., Schröder, R., Noegel, A.A. & Clemen, C.S. (2009)
Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle.
J. Mol. Biol. 393, 287-299.
DOI | PubMed |
33. Laohavisit, A., Mortimer, J.C., Demidchik, V., Coxon, K.M., Stancombe, M.A., Macpherson, N., Brownlee, C., Hofmann, A., Webb, A.A.R., Miedema, H., Battey, N.H. & Davies, J.M. (2009)
Zea mays annexins modulate cytosolic free Ca2+ and generate a Ca2+-permeable conductance.
Plant Cell 21, 479-493.
DOI | PubMed | Publisher |
32. Wang, Y.-Q., Feechan, A., Yun, B.-W., Shafiei, M., Hofmann, A., Taylor, P., Xue, P., Yang, F.-Q., Xie, Z.-S., Pallas, J.A., Chu, C.-C. & Loake, G. (2009)
S-nitrosylation of AtSABP3 antagonizes the expression of plant immunity.
J. Biol. Chem. 284, 2131-2137.
DOI | PubMed | PDF |
31. Hofmann, A. (2009)
ACDP - a Java application for data processing and analysis of protein circular dichroism spectra.
J. Appl. Crystallogr. 42, 137-139.
DOI | More |
30. Hu, N.-J., Yusof, A. M., Winter, A., Osman, A., Reeve, A. K. & Hofmann, A. (2008)
The crystal structure of calcium-bound annexin Gh1 from Gossypium hirsutum and its implications for membrane binding mechanisms of plant annexins.
J. Biol. Chem. 283, 18314-18322.
DOI | PubMed | PDF | Publisher | More |
29. Hu, N.-J., Bradshaw, J., Lauter, H., Buckingham, J., Solito, E. & Hofmann, A. (2008)
Membrane-induced folding and structure of membrane-bound annexin A1 N-terminal peptides - Implications for annexin-induced membrane aggregation.
Biophys. J. 94, 1773-1781.
DOI | PubMed | PDF | Publisher | More |
28. Rosentreter, A., Hofmann, A., Xavier, C.-P., Stumpf, M., Noegel, A.A. & Clemen, C.S. (2007)
Coronin 3 involvement in F-actin -dependent processes at the cell cortex.
Exp. Cell Res. 313, 878-895.
DOI | PubMed | PDF | More |
27. Winter, A., Kämäräinen, O. & Hofmann, A. (2007)
Molecular modelling of prohibitin domains.
Proteins 68, 353-362.
DOI | PubMed | PDF | More |
26. Hübbers, C.U., Clemen, C.S., Kesper, K., Böddrich, A., Hofmann, A., Kämäräinen, O., Tolksdorf, K., Stumpf, M., Reichelt, J., Roth, U., Krause, S., Watts, G., Kimonis, V., Wattjes, M.P., Reimann, J., Thal, D.R., Biermann, K., Evert, B.O., Lochmüller, H., Wanker, E.E., Schoser, B.G.H., Noegel, A.A. & Schröder, R. (2007)
Pathological consequences of VCP-mutations on human striated muscle.
Brain 130, 381-393.
DOI | PubMed | PDF | More |
25. Yusof, A.M., Jaenicke, E., Pedersen, J.S., Noegel, A.A., Schleicher, M. & Hofmann, A. (2006)
Mechanism of oligomerisation of cyclase-associated protein from Dictyostelium discoideum in solution.
J. Mol. Biol. 362, 1072-1081.
DOI | PubMed | PDF | More |
24. Winter, A., Yusof, A.M., Gao, E., Yan, H.L. & Hofmann, A. (2006)
Biochemical characterisation of annexin B1 from Cysticercus cellulosae.
FEBS J. 273, 3238-3247.
DOI | PubMed | PDF | Publisher | More |
23. Dabitz, N., Hu, N.-J., Yusof, A., Tranter, N., Winter, A., Daley, M., Zschörnig, O., Brisson, A. & Hofmann, A. (2005)
Structural determinants for plant annexin -membrane interactions.
Biochemistry 44, 16292-16300.
DOI | PubMed | PDF |
22. Yusof, A.M., Hu, N.-J., Wlodawer, A. & Hofmann, A. (2005)
Structural evidence for variable oligomerisation of the N-terminal domain of cyclase-associated protein (CAP).
Proteins 58, 255-262.
DOI | PubMed | Publisher | More |
21. Hofmann, A., Delmer, D.P. & Wlodawer, A. (2003)
The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster - Implications for cellulose synthase complex formation and oxidative stress response.
Eur. J. Biochem. 270, 2557-2564.
DOI | PubMed | PDF | More |
20. Hofmann, A., Hess, S., Noegel, A., Schleicher, M. & Wlodawer, A. (2002)
Crystallisation of cyclase associated protein from Dictyostelium discoideum.
Acta Crystallogr. D 58, 858-1861.
DOI | PubMed | PDF |
19. Hofmann, A., Iwai, H., Hess, S., Plückthun, A. & Wlodawer, A. (2002)
Crystal structure of cyclised green fluorescent protein.
Acta Crystallogr. D 58, 1400-1406.
DOI | PubMed | PDF |
18. Hofmann, A., Ruvinov, S., Hess, S., Schantz, R., Delmer, D.P. & Wlodawer, A. (2002)
Plant annexins form calcium-independent oligomers in solution.
Protein Sci. 11, 2033-2040.
DOI | PubMed | PDF |
17. Hofmann, A., Tarasov, S., Grella, M., Ruvinov, S., Nasr, F., Filipowicz, W. & Wlodawer, A. (2002)
Biophysical characterisation of cyclic nucleotide phosphodiesterases.
Biochem. Biophys. Res. Comm. 291, 875-883.
DOI | PubMed | PDF |
16. Hofmann, A., Grella, M., Botos, I., Filipowicz, W. & Wlodawer, A. (2002)
Crystal structures of the semi-reduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana.
J. Biol. Chem. 277, 1419-1425.
DOI | PubMed | PDF |
15. Hofmann, A. & Wlodawer, A. (2002)
PCSB - a programme collection for structural biology and biophysical chemistry.
Bioinformatics 18, 209-210.
DOI | PubMed | PDF | More |
14. Dorowski, A., Hofmann, A., Steegborn, C., Boicu, M. & Huber, R. (2001)
Crystal structure of paprika ferredoxin-NADP+ reductase - implications for the electron transfer pathway.
J. Biol. Chem. 276, 9253-9263.
DOI | PubMed | PDF | Publisher |


Letters and Communications
2. Hu, N.-J., Currid, M., Daley, M. & Hofmann, A. (2005)
Two new software applications for automated processing of circular dichroism and fluorescence data.
Appl. Spectrosc. 59, 68A.
Publisher | More


Reviews
25. Cross, M., Klepzig, E., Dallaston, M., Young, N.D., Bailey, U.-M., Mason, L., Jones, M.K., Gasser, R.B. & Hofmann, A. (2016)
Exploring the molecular mechanisms of parasite-host interactions with a view towards new therapeutics and vaccines.
Postepy Biochemii 62, 370-376.
PubMed | Publisher | More |
24. Mohandas, N., Young, N.D., Abdul, J., Korhonen, P.K., Koehler, A.V., Hall, R.S., Hu, M., Hofmann, A. & Gasser, R.B. (2016)
The complement of family M1 aminopeptidases of Haemonchus contortus - biotechnological implications.
Biotechnol. Advances 34, 65-76.
DOI | PubMed | More |
23. Mohandas, N., Young, N.D., Jabbar, A., Korhonen, P.K., Koehler, A.V., Amani, P., Hall, R.S., Sternberg, P.W., Jex, A.R., Hofmann, A. & Gasser, R.B. (2015)
The barber's pole worm CAP protein superfamily - a basis for fundamental discovery and biotechnology advances.
Biotechnol. Advances 33, 1744-1754.
DOI | PubMed | More |
22. Sarnpitak, P., Mujumdar, P., Taylor, P., Cross, M., Coster, M., Gorse, A.-D., Krasavin, M. & Hofmann, A. (2015)
Panel docking of small-molecule libraries — prospects to improve efficiency of lead compound discovery.
Biotechnol. Advances 33, 941-947.
DOI | PubMed | More |
21. Cantacessi, C., Hofmann, A., Campbell, B.E. & Gasser, R.B. (2015)
Impact of next-generation technologies on exploring socioeconomically important parasites and developing new interventions.
In Veterinary Infection Biology: Molecular Diagnostics and High-Throughput Strategies, Methods in Molecular Biology, vol 1247 (Cunho, M. & Inacio, J., edts.), Springer, New York, 437-474.
DOI | PubMed | More |
20. Mason, L., Amani, P., Cross, M., Baker, J., Bailey, U.-M., Jones, M.K., Gasser, R.B. & Hofmann, A. (2014)
The relevance of structural biology in studying molecules involved in parasite-host interactions - potential for designing new interventions.
Aust. J. Chem. 67, 1732-1740.
DOI | More |
19. Leow, C.Y., Willis, C., Hofmann, A. & Jones, M.K. (2015)
Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control.
Br. J. Pharmacol. 172, 1653-1663.
DOI | PubMed | More |
18. Ansell, B.R., Schnyder, M., Deplazes, P., Korhonen, P.K., Young, N.D., Hall, R.S., Mangiola, S., Boag, P.R., Hofmann, A., Sternberg, P.W., Jex, A.R. & Gasser, R.B. (2013)
Insights into the immuno-molecular biology of Angiostrongylus vasorum through transcriptomics - prospects for new interventions.
Biotechnol. Advances 31, 1486-1500.
DOI | PubMed | More |
17. Osman, A., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R.B. & Hofmann, A. (2012)
Hookworm SCP/TAPS protein structure - a key to understanding host-parasite interactions and developing new interventions.
Biotechnol. Advances 30, 652-657.
DOI | PubMed | More |
16. Konopka-Postupolska, D., Clark, G. & Hofmann, A. (2011)
Structure, function and membrane interactions of plant annexins: an update.
Plant Sci. 181, 230-241.
DOI | PubMed | More |
15. Kellenberger, E., Hofmann, A. & Quinn, R. (2011)
Similar interactions of natural products with biosynthetic enzymes and therapeutic targets explain why nature produces such a large proportion of existing drugs.
Nat. Prod. Reports 28, 1483-1492.
DOI | PubMed | More |
14. Gasser, R.B., Cantacessi, C., Campbell, B.E., Hofmann, A. & Otranto, D. (2011)
Major prospects for exploring canine vector borne diseases and novel intervention methods using 'omic technologies.
Parasites & Vectors 4, 53.
DOI | PubMed | PDF | Publisher | More |
13. Campbell, B.E., Boag, P.R., Hofmann, A., Cantacessi, C., Wang, C.K., Taylor, P., Hu, M., Sindhu, Z., Loukas, A., Sternberg, P.W. & Gasser, R.B. (2011)
Atypical (RIO) protein kinases from Haemonchus contortus — Promise as new targets for nematocidal drugs.
Biotechnol. Advances 29, 338-350.
DOI | PubMed | More |
12. Campbell, B.E., McCluskey, A., Hofmann, A. & Gasser, R.B. (2011)
Serine/threonine phosphatases in socioeconomically important parasitic nematodes - prospects as novel drug targets?
Biotechnol. Advances 29, 28-39.
DOI | PubMed | More |
11. Hofmann, A., Wang, C.K., Osman, A. & Camp, D. (2010)
Merging Structural Biology with Chemical Biology: Structural Chemistry at Eskitis.
Struct. Chem. 21, 1117-1129.
DOI | Publisher | More |
10. Hofmann, A., Osman, A., Leow, C.Y., Driguez, P., McManus, D.P. & Jones, M.K. (2010)
Parasite annexins - new molecules with potential for drug and vaccine development.
BioEssays 32, 967-976.
DOI | PubMed | PDF | Publisher | More |
9. Cantacessi, C., Campbell, B.E., Visser, A., Geldhof, P., Nolan, M.J., Nisbet, A.J., Matthews, J.B., Loukas, A., Hofmann, A., Otranto, D., Sternberg, P.W. & Gasser, R.B. (2009)
A portrait of the SCP/TAPS proteins of eukaryotes - developing a framework for fundamental research and biotechnological outcomes.
Biotechnol. Advances 27, 376-388.
DOI | PubMed |
8. McArdle, B. & Hofmann, A. (2008)
Coronin Structure and Implications.
In The Coronin Family of Proteins (Clemen, C., Eichinger, L., Rybakin, V., edt.), Landes Bioscience, Georgetown, Texas, 56-71.
DOI | PubMed | PDF | Publisher |
7. Winter, A. & Hofmann, A. (2008)
Towards understanding the roles of prohibitins, multi-functional regulator proteins.
Curr. Chem. Biol. 2, 11-19.
DOI | Publisher |
6. Braunewell, K.-H., Brackmann, M. & Hofmann, A. (2006)
VILIP-1, a novel regulator of the guanylate cyclase transduction system in neurons.
Calcium-binding Proteins 1, 12-15.
Publisher
5. Brackmann, M., Hofmann, A. & Braunewell, K.-H. (2006)
Structure, function and expression of members of the VILIP (visinin-like protein) subfamily of neuronal calcium sensor proteins.
In Neuronal calcium sensor proteins - Molecular Anatomy and Physiology of Proteins (Uversky, V., Koch, K.-W., Phillipov, P., edt.), Nova Science Publishers, 115-135.
Publisher
4. Hofmann, A. (2004)
Annexins in the plant kingdom: perspectives and potentials.
Annexins 1, 51-61.
PDF | Publisher | More
3. Hofmann, A. & Huber, R. (2003)
Liposomes in assessment of annexin-membrane interactions.
In Methods Enzymol., 372, 186-216.
PubMed |
2. Hofmann, A. & Huber, R. (2003)
Structural conservation and functional versatility: Allostery as a common annexin feature.
In Annexins: Biological Importance and Annexin-Related Pathologies (Bandorowicz-Pikula, J., edt.), Landes Bioscience, Georgetown, Texas, 38-60.
Publisher


Textbooks
8. Hofmann, A. (2016)
Introduction to Physical Chemistry.
2nd edition, Structural Chemistry Program, Griffith University, Brisbane, Australia.
Publisher | More
7. Hofmann, A. (2016)
Methods in Structural Chemistry - A Lab Manual.
3rd edition, Structural Chemistry Program, Griffith University, Brisbane, Australia.
Publisher | More
5. Hofmann, A. (2015)
Methods in Structural Chemistry - A Lab Manual.
2nd edition, Structural Chemistry Program, Griffith University, Brisbane, Australia.
Publisher | More
4. Hofmann, A., Simon, A., Grkovic, T. & Jones, M.K. (2014)
Methods of Molecular Analysis in the Life Sciences.
Cambridge University Press, Cambridge, UK.
Publisher | More
3. Hofmann, A. (2014)
Methods in Structural Chemistry - A Lab Manual.
1st edition, Structural Chemistry Program, Griffith University, Brisbane, Australia.
More
2. Hofmann, A. (2010)
Spectroscopic Techniques: II Structure and Interactions.
In Principles and Techniques of Biochemistry and Molecular Biology (Wilson, K., Walker, J.M., edt.), 7th edition, Cambridge University Press, Cambridge, UK, 522-552.
Publisher | More
1. Hofmann, A. (2010)
Spectroscopic Techniques: I Spectrophotometric Techniques.
In Principles and Techniques of Biochemistry and Molecular Biology (Wilson, K., Walker, J.M., edt.), 7th edition, Cambridge University Press, Cambridge, UK, 477-521.
Publisher | More


Doctoral Theses
4. Osman, A. (2012)
Structural and functional investigation of two parasite protein systems, alpha giardins from Giardia lamblia and pathogenesis-related proteins from Ancylostoma caninum.
PhD Thesis, Griffith University.


Diploma and Masters Theses
6. Paul, B.A. (2011)
Structure-based drug design for carbonic anhydrases and membrane interactions of human Visinin-like Protein 1.
MPhil Thesis, Griffith University.
4. Kämäräinen, O. (2007)
Molecular mechanisms of proteins involved in signal transduction and inflammation.
MSc Thesis, The University of Edinburgh.


Conference Reports
85. Cross, M., Lepage, R., Rajan, S., Biberacher, S., Young, N.D., Kim, B.-N., Coster, J., Gasser, R.B., Kim, J.-S. & Hofmann, A. (2017)
Probing function and structure of trehalose-6-phosphate phosphatases suggests distinct molecular groupings.
42nd Lorne Conference on Protein Structure and Function, 5-9 Feb 2017, Lorne, Victoria, Australia.
84. Young, N.D., Chan, K.-G., Korhonen, P.K., Chong, T.M., Ee, R., Mohandas, N., Koehler, A.V., Lim, Y.-L., Hofmann, A., Jex, A.R., Qian, B., Chilton, N.B., Gobert, G.N., McManus, D.P., Tan, P., Webster, B.L., Rollinson, D. & Gasser, R.B. (2016)
Exploring molecular variation in Schistosoma japonicum in China.
XIX. International Congress for Tropical Medicine and Malaria (ICTMM), 18-22 Sep 2016, Brisbane, Australia.
83. Hofmann, A. (2015)
Chemical probing of mycobacterial carbonic anhydrases suggests Redox-regulation and provides an avenue for non-classical inhibitors.
ComBio 2015, 27 Sep - 1 Oct, 2015, Melbourne, Australia.
82. Ströhlein, A.J., Young, N.D., Sternberg, P.W., Jex, A.R., Boag, P.R., Hofmann, A. & Gasser, R.B. (2015)
Defining the Schistosoma haematobium kinome as a basis for the prediction and prioritisation of kinases as anti-schistosome drug targets.
2015 NZSP & ASP Conference, 29 June-2 July, 2015, Auckland, New Zealand.
81. Preston, S., Jabbar, A., Nowell, C., Joachim, A., Ruttkowski, B., Baell, J., Cardno, T., Korhonen, P., Piedrafita, D., Ansell, B., Jex, A., Hofmann, A. & Gasser, R.B. (2015)
Low cost whole-organism compound screening method.
2015 NZSP & ASP Conference, 29 June-2 July, 2015, Auckland, New Zealand.
80. Anstead, C.A., Korhonen, P.K., Young, N.D., Hall, R.S., Jex, A.R. Murali, S.C., Hughes, D.S.T., Lee, S.F., P.T., Ströhlein, A.J., Ansell, B.R.E, Breugelmans, B., Hofmann, A., Qu, J., Dugan, S., Lee, S. L., Chao, H., Dinh, H. & Gasser, R.B. (2015)
Lucilia cuprina genome and transcriptomes — critical resources to underpin biological investigations and biotechnological outcomes.
2015 NZSP & ASP Conference, 29 June-2 July, 2015, Auckland, New Zealand.
79. Breugelmans, B., Jex, A.R., Korhonen, P.K., Young, N.D., Sternberg, P.W., Boag, P.R., Hofmann, A. & Gasser, R.B. (2014)
An exploration of RIO protein kinases of parasitic and free-living nematodes - prospects for drug design.
2014 ASP Annual Conference, 30 June-3 July, 2014, ANU Commons, Canberra, Australia.
78. Korhonen, P.K., Zhu, X., Young, N.D., Cai, H., Nejsum, P., Jex, A., von Samson-Himmelstjerna, G., Hall, R.S., Fang, X., Hofmann, A., Sternberg, P.W. & Gasser, R.B. (2014)
Cracking the code of Toxocara canis and its implication.
2014 ASP Annual Conference, 30 June-3 July, 2014, ANU Commons, Canberra, Australia.
77. Young, N.D., Nagarajan, N., Lin, S.J., Korhonen, P.K., Jex, A.R., Hall, R.S., Safavi-Hemami, H., Hofmann, A., Kaewkong, W., Bertrand, D., Gao, S., Seet, Q., Wongkham, S., Teh, B.T., Wongkham, C., Intapan, P.M., Maleewong, W., Yang, X., Hu, M., Wang, Z., Sternberg, P.W., Tan, P., Wang, J. & Gasser, R.B. (2014)
The Opisthorchis viverrini genome provides insights into life in the bile duct.
2014 ASP Annual Conference, 30 June-3 July, 2014, ANU Commons, Canberra, Australia.
76. Leow, C.Y., Willis, C., Osman, A., Mason, L., Simon, A., Gasser, R.B., Smith, B., Jones, M.K. & Hofmann, A. (2014)
Crystal structure and immunological properties of the first annexin from Schistosoma mansoni - Insights into the structural integrity of the schistosomal tegument.
Crystal 29, 22-25 April 2014, O'Reilly's, Australia.
75. Weeratunga, S., Osman, A., Hu, N.-J., Wang, C., Svärd, S., Jones, M.K. & Hofmann, A. (2014)
alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.
39th Lorne Conference on Protein Structure and Function, 9-13 Feb 2014, Lorne, Australia.
74. Ansell, B.R., Schnyder, M., Deplazes, P., Korhonen, P.K., Young, N.D., Hall, R.S., Mangiola, S., Boag, P.R., Hofmann, A., Sternberg, P.W., Jex, A.R. & Gasser, R.B. (2013)
Insights into the immuno-molecular biology of Angiostrongylus vasorum through transcriptomics-Prospects for new interventions.
Proceedings 2013 World Association for the Advancement of Veterinary Parasitology (WAAVP), 25-29 Aug 2013, Perth, Australia.
73. Breugelmans, B., Mondal, A., Boag, P.R., Hofmann, A., Jex, A.R. & Gasser, R.B. (2013)
RIO kinases of parasitic nematodes.
Proceedings 2013 World Association for the Advancement of Veterinary Parasitology (WAAVP), 25-29 Aug 2013, Perth, Australia.
72. Schwarz, E.M., Korhonen, P.K., Campbell, B.E., Young, N.D., Jex, A.R., Jabbar, A., Hall, R.S., Mondal, A., Howe, A.C., Pell, J., Hofmann, A., Boag, P.R., Zhu, X.Q., Gregory, T.R., Loukas, A., Williams, B.A., Antoshechkin, I., Brown, C.T., Sternberg, P.W. & Gasser, R.B. (2013)
The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus.
Proceedings 2013 World Association for the Advancement of Veterinary Parasitology (WAAVP), 25-29 Aug 2013, Perth, Australia.
70. Weeratunga, S., Osman, A., Hu, N.-J., Wang, C., Svärd, S., Jones, M.K. & Hofmann, A. (2013)
alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.
38th Lorne Conference on Protein Structure and Function, 10-14 Feb 2013, Lorne, Australia.
69. Walden, P., Weeratunga, S. & Hofmann, A. (2013)
SDAR: a practical tool for graphical analysis of two-dimensional data.
38th Lorne Conference on Protein Structure and Function, 10-14 Feb 2013, Lorne, Australia.
68. Weeratunga, S., Osman, A., Hu, N.-J., Wang, C., Svärd, S., Jones, M.K. & Hofmann, A. (2012)
alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.
Crystal 28 - 28th Meeting of the Society of Crystallographers in Australia and New Zealand (SCANZ), 2-6 Dec 2012, Adelaide, Australia.
67. Willis, C., Hofmann, A., Caffrey, C., Loukas, A. & Jones, M.K. (2012)
Why are Saposin-like proteins so ubiquitous, what is their function?.
XVIII International Congress for Tropical Medicine and Malaria, 23-28 Sept 2012, Rio de Janeiro, Brazil.
66. Willis, C., Hofmann, A., Caffrey, C., Loukas, A. & Jones, M.K. (2012)
Why are Saposin-like proteins so ubiquitous, what is their function?.
13th International Symposium on Schistosomiasis, 16-19 Sept 2012, Associacao Medica de Minas Gerais, Brazil.
65. Cantacessi, C., Loukas, A., Hofmann, A., Young, N.D., Broder, U. & Gasser, R.B. (2012)
SCP/TAPS proteins of parasitic helminths - future prospects.
Molecular and Cellular Biology of Helminth Parasites VII, 2-7 Sept 2012, Hydra, Greece.
64. Leow, Y., Willis, C., Loukas, A., Hofmann, A. & Jones, M. (2012)
Epitope-based immuno-informatics and immunological characterisation of annexin as a novel vaccine candidate for schistosomiasis.
2012 Australian Society for Parasitology Annual Conference, 2-5 July 2012, Launceston, Tasmania, Australia.
63. Young, N.D., Jex, A.R., Li, B., Liu, S., Yang, L., Xiong, Z., Li, Y., Cantacessi, C., Hall, R.S., Xu, X., Chen, F., Wu, X., Zerlotini, A., Oliveira, G., Hofmann, A., Zhang, G., Fang, X., Kang, Y., Campbell, B.E., Loukas, A., Ranganathan, S., Rollinson, D., Rinaldi, G., Brindley, P.J., Yang, H., Wang, J., Wang, J. & Gasser, R.B. (2012)
A Schistosoma haematobium draft genome: a resource for fundamental and applied research on urogenital schistosomiasis.
2012 Australian Society for Parasitology Annual Conference, 2-5 July 2012, Launceston, Tasmania, Australia.
62. Wang, C.K., Broder, U., Weeratunga, S., Gasser, R.B., Loukas, A. & Hofmann, A. (2012)
SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments.
37th Lorne Conference on Protein Structure and Function, 5-9 Feb 2012, Lorne, Australia.
61. Osman, A., Pacheco, C.M., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R.B. & Hofmann, A. (2012)
Hookworm SCP/TAPS protein structure - a key to understanding host-parasite interactions and developing new interventions.
37th Lorne Conference on Protein Structure and Function, 5-9 Feb 2012, Lorne, Australia.
60. Wang, C.K. (2011)
A tale of two neuronal proteins - some structural insights.
South East Queensland Structural Biology Forum, 2 Dec 2011, Queensland Biosciences Precinct, Australia.
59. Hofmann, A. (2011)
Towards understanding the molecular mechanisms of helminth saposin-like proteins.
South East Queensland Structural Biology Forum, 2 Dec 2011, Queensland Biosciences Precinct, Australia.
58. Osman, A., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R.B. & Hofmann, A. (2011)
The crystal structure of a novel Ancylostoma-secreted protein and its implications for exploring host-protein interactions.
ComBio 2011, 25-29 Sept 2011, Cairns, Qld, Australia.
56. Nolan, M.J., Hofmann, A., Jex, A.R. & Gasser, R.B. (2011)
Point mutations in triose-phosphate isomerase of Giardia duodenalis: RedOx dependency of catalytic activity and support for the neutral theory of evolution.
36th Lorne Conference on Protein Structure and Function, 6-10 Feb 2011, Lorne, Australia.
55. Hofmann, A., Wang, C.K., Taylor, P., Campbell, B.E., Boag, P.R., Cantacessi, C., Hu, M., Sindhu, Z., Loukas, A., Sternberg, P.W. & Gasser, R.B. (2011)
Comparative modelling and virtual screening of atypical (RIO) protein kinases from Haemonchus contortus - promise as new targets for nematocidal drugs.
36th Lorne Conference on Protein Structure and Function, 6-10 Feb 2011, Lorne, Australia.
54. Wang, C.K., Jessen, C.M., Oliveira, C.L.P., Pedersen, J.S. & Hofmann, A. (2011)
The low-resolution structure of Visinin-like Protein 1 and its implications for a hetero-tetrameric complex with guanylyl cyclase.
36th Lorne Conference on Protein Structure and Function, 6-10 Feb 2011, Lorne, Australia.
53. Wang, C.K., Simon, A., Braunewell, K.-H. & Hofmann, A. (2011)
Interactions of Visinin-like Proteins with phospho-inositides with phospho-inositides.
36th Lorne Conference on Protein Structure and Function, 6-10 Feb 2011, Lorne, Australia.
52. Hofmann, A., Osman, A., Leow, C.Y., Driguez, P., McManus, D.P & Jones, M.K. (2011)
Parasite annexins - new molecules with potential as targets in infectious diseases.
36th Lorne Conference on Protein Structure and Function, 6-10 Feb 2011, Lorne, Australia.
51. Wang, C., Campbell, B.E., Taylor, P., Gasser, R.B. & Hofmann, A. (2010)
Atypical (RIO) protein kinases from Haemonchus contortus - Promise as new targets for nematocidal drugs.
South East Queensland Structural Biology Forum, 19 Nov 2010, Gold Coast, Qld, Australia.
50. Osman, A. & Hofmann, A. (2010)
Structure-function studies of annexins in infectious diseases.
OzBio2010 The Molecules of Life - from Discovery to Biotechnology, 26 Sept - 1 Oct 2010, Melbourne, Australia.
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49. Hofmann, A. (2010)
Structure-function relationships of proteins involved in infectious and neurological diseases.
GMRC Retreat, Griffith University and Queensland Institute for Medical Research, 27 Sept 2010, Brisbane, Australia.
48. Leow, Y., Willis, C., Loukas, A., Hofmann, A. & Jones, M. (2010)
Molecular characterisation of Schistosoma mansoni tegument annexin - towards development of a novel vaccine.
XIIth International Congress of Parasitology, 15-20 Aug 2010, Melbourne, Australia.
47. Nolan, M. J., Jex, A. R., Hofmann, A., Campbell, A. J., Stevens, M. & Gasser, R. B. (2010)
Genetic characterisation of Giardia duodenalis from Australian sheep - zoonotic implications?.
XIIth International Congress of Parasitology, 5-20 August, Melbourne, Australia.
46. Hofmann, A., Osman, A. & Jones, M. (2010)
Parasite annexins as novel targets in infectious diseases.
35th Lorne Conference on Protein Structure and Function, 7-11 Feb 2010, Lorne, Australia.