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Teaching
Update: 04.06.2009
TEACHING 2009
Structural Aspects of Medicinal Chemistry (SCE3153, BBS3018), 2009, Lectures
Lectures 03.04.2009: X-ray Crystallography
Structural Chemistry Methods, 2009, Workshop
Session 01, 16.01.2009: Crystal Lattices
Session 02, 23.01.2009: Bravais Lattices
Session 03, 30.01.2009: Geometry of X-ray Diffraction
Session 04, 13.02.2009: X-ray Diffraction
Session 05, 20.02.2009: Miller Indices
Session 06, 27.02.2009: Reciprocal Lattice
Session 07, 06.03.2009: Reciprocal Lattice
Session 08, 13.03.2009: Symmetry elements
Session 09, 20.03.2009: Crystal Lattices
Session 10, 03.04.2009: Protein X-ray Crystallography: Basic Overview
Session 11, 09.04.2009: Diffraction Intensities
Session 12, 24.04.2009: Crystallography Quiz
Session 13, 01.05.2009: Crystallography Quiz
Session 14, 08.05.2009: Space Group Determination
Session 15, 15.05.2009: Space Group Determination
Session 16, 29.05.2009: Space Group Determination
Session 17, 05.06.2009: Space Group Determination
Structural Chemistry Computing, 2009, Workshop
Session 01, 15.01.2009: Manipulation of serial data with SDAR
Session 02, 22.01.2009: The 2008 Lindau Nobel Laureate Meeting
Session 03, 29.01.2009: Crystallographic calculations
Session 04, 12.02.2009: Symmetry matrices
Session 05, 19.02.2009: CV writing
Session 06, 26.02.2009: 1. Risk Assessments, 2. Chaotic Proteins
Session 07, 05.03.2009: Crystallographic calculations
Session 08, 19.03.2009: Terminology
Session 09, 02.04.2009: MALS analysis with Astra
Session 10, 17.04.2009: Indexing with Mosflm
Session 11, 28.05.2009: Molecular graphics with Sirius
Session 12, 04.06.2009: Molecular graphics with UCSF Chimera
TEACHING 2008
Drug Discovery, Metabolism & Delivery (SCE3142), 2008, Lectures
Lecture 22.09.2008: Basic Principles of Molecular Modelling
Lecture 24.09.2008: Molecular Modelling: Basic Applications
Structural Aspects of Medicinal Chemistry (SCE3153, BBS3018), 2008, Lectures
Lectures 10.04.2008: X-ray Crystallography
Structural Chemistry Computing, 2008, Workshop
Session 01, 10.01.2008: Protein Ligand Docking
Session 02, 17.01.2008: Protein Ligand Docking
Session 03, 24.01.2008: Basic Principles of Molecular Modelling
Session 04, 07.02.2008: Protein Ligand Docking
Session 05, 27.03.2008: UNIX shell commands
Session 06, 03.04.2008: Molecular Visualisation with PyMOL
Session 07, 10.04.2008: Manipulation of structured data with awk
Session 08, 08.05.2008: Practical calculations
Session 09, 15.05.2008: Stoichiometric calculations
Session 10, 23.05.2008: Molecular graphics with O
Session 11, 29.05.2008: Molecular graphics with Coot
Session 12, 03.06.2008: Diffraction data processing with Mosflm
Session 13, 05.06.2008: Analysis of amino acid sequence alignment with JalView
Session 14, 12.06.2008: Diffraction data reduction with Scala
Session 15, 26.06.2008: Crystallographic refinement with CNS
Session 16, 03.07.2008: Molecular replacement with AMoRe
Session 17, 10.07.2008: Molecular replacement with AMoRe
Session 18, 17.07.2008: Word processing with OpenOffice
Session 19, 07.08.2008: Word processing with OpenOffice
Session 20, 14.08.2008: Reference management with Bibus
Session 21, 04.09.2008: Introduction to UNIX commands
Session 22, 11.09.2008: UNIX commands
Session 23, 19.09.2008: Manipulation of structured data with awk
Session 24, 26.09.2008: Homology modelling with Modeller
Session 25, 09.10.2008: Crystallographic calculations
Session 26, 23.10.2008: The EMBOSS suite
Session 27, 30.10.2008: Homology modelling with Modeller
Session 28, 06.11.2008: Molecular graphics using Sirius
Structural Chemistry Methods, 2008, Workshop
Session 01, 28.03.2008: Crystallography I: Introduction to Symmetry
Session 02, 11.04.2008: Crystallography II: Translational Symmetry Elements, Coordinate Systems, and Symmetry Calculations
Session 03, 22.04.2008: Crystallography III: Point Groups (Crystal Classes), Bravais Lattice, and Space Groups
Session 04, 09.05.2008: Crystallography IV: X-rays, Diffraction, Bragg’s Law, and the Reciprocal Lattice
Session 05, 16.05.2008: Biochemical buffers
Session 06, 30.05.2008: Protein Architecture I
Session 07, 06.06.2008: Protein Architecture II
Session 08, 13.06.2008: Protein Architecture III
Session 09, 20.06.2008: Crystallography Quiz
Session 10, 20.06.2008: Centrifugation
Session 11, 27.06.2008: Crystallography V: Ewald Sphere, Structure Factor Equation
Session 12, 04.07.2008: Crystallography VI: Intensities of Reflections, Electron Density
Session 13, 17.07.2008: Crystallographic data processing
Session 14, 24.07.2008: Crystallographic data processing
Session 15, 08.08.2008: Fluorescence spectroscopy I
Session 16, 15.08.2008: Fluorescence spectroscopy II
Session 17, 21.08.2008: Studies on Annexin Structure-Function Relationships
Session 18, 29.08.2008: Crystallographic Symmetry
Session 19, 05.09.2008: Crystallographic Symmetry
Session 20, 12.09.2008: Symmetry Elements and Coordinate Systems
Session 21, 18.09.2008: Symmetry Elements and Coordinate Systems
Session 22, 26.09.2008: Coordinate Systems and Crystal Classes
Session 23, 03.10.2008: Crystal Systems, Coordinate Systems
Session 24, 10.10.2008: Bravais Lattices
Session 25, 24.10.2008: Space group determination
Session 26, 31.10.2008: Reflection Intensities
Session 27, 04.11.2008: Space group determination
Session 28, 05.11.2008: Crystal symmetry
TEACHING 2007
Drug Discovery, Metabolism & Delivery (SCE3142), 2007, Lectures
Lecture, 10.09.2007: Basic Principles of Molecular Modelling
Lecture, 13.09.2007: Basic Applications of Molecular Modelling
Structural Chemistry Methods, 2007, Workshop
Session 01, 07.09.2007: Crystallography I: Introduction to Symmetry
Session 02, 14.09.2007: Spectroscopy I: CD Spectroscopy
Session 03, 21.09.2007: Crystallography II: Translational Symmetry Elements, Coordinate Systems, and Symmetry Calculations
Session 04, 12.10.2007: Subcloning of protein constructs
Session 05, 26.10.2007: Biochemical buffers
Session 06, 16.11.2007: Crystallography III: Point Groups (Crystal Classes), Bravais Lattice, and Space Groups
Session 07, 23.11.2007: Crystallography IV: X-rays, Diffraction, Bragg’s Law, and the Reciprocal Lattice
Session 08, 30.11.2007: Crystallography V: Ewald Sphere, Structure Factor Equation
Session 09, 07.12.2007: Crystallography VI: Intensities of Reflections, Electron Density
Structural Chemistry Computing, 2007, Workshop
Session 01, 24.05.2007: UNIX Shell Commands
Session 02, 14.06.2007: Manipulation of Structured Data with 'awk'
Session 03, 05.07.2007: Molecule superposition with Uppsala software ('lsqman')
Session 04, 26.07.2007: Shell Programming: Molecule Superposition with Uppsala Software ('lsqman', 'moleman')
Session 05, 16.08.2007: Structural alignment with 'lsqman'
Session 06, 06.09.2007: Structure Visualisation with 'PyMOL'
Session 07, 20.09.2007: The Linux environment in Structural Chemistry
Session 08, 11.10.2007: UNIX shell commands
Session 09, 25.10.2007: Introduction to 'Sybyl'
Session 10, 15.11.2007: Structure visualisation with AstexViewer and RasMol
Session 11, 22.11.2007: Space group determination
Session 12, 29.11.2007: Space Group Determination
Session 13, 06.12.2007: Space Group Determination with Mosflm
Session 14, 13.12.2007: Space group determination
Session 15, 20.12.2007: Protein homology modelling
TEACHING 2006/2007
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2006-2007, Tutorials
Tutorial 2, 02.10.06: Assignment of, introduction to and guidance on assessed course work
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2006-2007, Lectures
Lecture 3, 28.09.06: Macromolecules 2: Protein Architecture
Lecture 4, 02.10.06: Macromolecules 3: X-ray crystallography
TEACHING 2005/2006
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2005-2006, Tutorials
Tutorial 1, 26.09.05: Amino acid structures, primary/secondary structure, spectroscopy, peptide synthesis
Tutorial 2, 03.10.05: Assignment of, introduction to and guidance on assessed course work
Tutorial 3, 17.10.05: Protein Folding
Tutorial 4, 31.10.05: Protein Interactions
Tutorial 5, 14.11.05: Enzyme Mechanisms
Tutorial 6, 28.11.05: Membrane Structure
Molecular Biology Honours: Structural Biology, 2005-2006, Data Interpretation
Data Interpretation, 02.11.05: Structure of the N-terminal domain of Adenylyl Cyclase -Associated Protein
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2005-2006, Lectures
Lecture 3, 29.09.05: Macromolecules 2: Protein Architecture
Lecture 4, 03.10.05: Macromolecules 3: X-ray crystallography
Biotechnology Honours: Enzymology, 2005-2006, Lectures
Enzymology 4, 04.10.05: Enzyme Encapsulation
Enzymology 5, 04.10.05: Membrane Enzymes
Biological Sciences Honours: Structural Biology, 2005-2006, Lectures
Structural Biology 06, 11.10.05: The structural basis of transcription: RNA polymerase II
Structural Biology 13, 15.11.05: The structural basis of translation: The ribosome
Structural Biology: Studying Macromolecules in Health and Disease, 2005-2006, Electives
Session 01, 20.09.05: Lecture: Introduction, General Comments, UV/Vis Spectroscopy
Session 02, 27.09.05: Lecture: Fluorescence Spectroscopy 1
Session 03, 04.10.05: Practical: Peptide properties
Session 04, 11.10.05: Lecture: Fluorescence spectroscopy 2
Session 05, 18.10.05: Paper presentations
Session 06, 25.10.05: Lecture: CD Spectroscopy
Session 07, 01.11.05: Practical: CD Spectroscopy
Session 08, 08.11.05: Paper presentations
Session 09, 15.11.05: Practical: Fluorescence spectrosocpy
Session 10, 22.11.05: Practical: Fluorescence spectrosocpy
Session 11, 29.11.05: Problem session
TEACHING 2004/2005
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2004-2005, Tutorials
Tutorial 1, 27.09.04:
Amino acids, peptide bonds, spectroscopy
Tutorial 2, 04.10.04:
Assignment of assessed course work
Tutorial 3, 18.10.04:
Protein Folding and Structure Determination
Tutorial 4, 01.11.04:
Quaternary structure, Histones, Polyelectrolyte theory
Tutorial 5, 15.11.04:
Enzyme Mechanisms
Tutorial 6, 29.11.04:
Membrane Structure
Molecular Biology Honours: Structural Biology, 2004-2005, Data Interpretation
Session 03.11.04:
Structural biology of cyclase-associated protein
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2004-2005, Lectures
Lecture 3, 30.09.04:
Protein Architecture
Lecture 4, 04.10.04:
Protein Crystallography
Biological Sciences Honours: Structural Biology, 2004-2005, Lectures
Structural Biology 06, 12.10.04:
The Structural Basis of Transcription: RNA Polymerase II
Structural Biology 13, 16.11.04:
The Structural Basis of Translation: The ribosome and protein synthesis
Biotechnology Honours: Enzymology, 2004-2005, Lectures
Enzymology 5, 05.10.04:
Membrane Enzymes
Enzymology 6, 05.10.04:
Enzyme Encapsulation
Structural Biology: Studying Macromolecules in Health and Disease, 2004-2005, Electives
Session 1, 05.10.04:
Lecture: Introduction, General Comments, UV/Vis Spectroscopy
Session 2, 12.10.04:
Practical: Peptide Properties; Lecture: Fluorescence Spectroscopy 1
Session 3, 19.10.04:
Paper Presentations; Lecture: Fluorescence Spectroscopy 2
Session 4, 26.10.04:
Paper Presentations; Lecture: Fluorescence Spectroscopy 3
Session 5, 02.11.04:
Lecture: CD Spectroscopy; Practical: Analysis of CD spectra
Session 6, 09.11.04/16.11.04:
Practical: Fluorescence Spectrosocpy
Session 7, 23.11.04:
Paper Presentations
TEACHING 2003/2004
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2003-2004, Tutorials
Tutorial T1, 10.10.03:
Amino acids, peptide bonds, spectroscopy
Tutorial T2, 31.10.03:
Protein Folding
Tutorial T3, 28.11.03:
Enzyme Mechanisms
Tutorial T4, 09.01.04:
Membrane Structure
Tutorial T5, 23.01.04:
Bioenergetics
Biochemistry/Molecular Biology Honours: Structural Biology, 2003-2004, Lectures
Structural Biology 8, 10.11.03:
The Structural Basis of Transcription: RNA Polymerase II
Structural Biology 9, 17.11.03:
The Structural Basis of Translation: The ribosome and protein synthesis
Biological Sciences 3rd year module: Structures and Functions of Proteins, 2003-2004, Lectures
Lecture 7, 24.10.03:
Protein X-ray Crystallography
(substituting for Malcolm Walkinshaw)
Biotechnology Honours: Enzymology, 2003-2004, Lectures
Enzymology 7, 05.11.03:
Membrane Enzymes
Enzymology 8, 05.11.03:
Enzyme Encapsulation
Structural Biology: Studying Macromolecules in Health and Disease, 2003-2004, Electives
Session 1, 06.01.04:
Lecture: Introduction, General Comments, UV/Vis Spectroscopy
Session 2, 08.01.04:
Practical: Amino Acid Properties
Session 3, 13.01.04:
Lecture: Fluorescence Spectroscopy 1
Session 4, 15.01.04:
Lecture: Fluorescence Spectroscopy 2, Practical: Titration Experiments
Session 5, 20.01.04:
Lecture: CD Spectroscopy, Practical: Analysis of CD spectra
Session 6, 22.01.04:
Paper discussion
Session 7, 27.01.04:
Practical: Fluorescence Experiment
TEACHING 2002/2003
Biological Sciences 3rd year module: Structure and Functions of Proteins, 2002-2003, Tutorials
Tutorial T1, 11.10.02:
Amino acids, peptide bonds, spectroscopy
Tutorial T2, 01.11.02:
Protein Folding
Tutorial T3, 29.11.02:
Enzyme Mechanisms
Tutorial T4, 10.01.03:
Membrane Structure
Tutorial T5, 24.01.03:
Bioenergetics
Biochemistry/Molecular Biology/Genetics Honours: Basis of Molecular Recognition, Core 2002-2003, Lectures
Lecture 8, 11.11.02:
The Structural Basis of Transcription: RNA Polymerase II
Lecture 9, 18.11.02:
The Structural Basis of Translation: The Ribosome and Protein Synthesis
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